Osteoclasts being more active than osteoblasts contributes to what change in bone with aging?

Sharpen your pharmacology and pathophysiology knowledge, focusing on hypertension, allergies, burns, and hair disorders. Utilize flashcards and multiple choice questions, each with hints and explanations, to prepare effectively for your exam.

Multiple Choice

Osteoclasts being more active than osteoblasts contributes to what change in bone with aging?

Explanation:
Bone remodeling is a balance between bone resorption by osteoclasts and bone formation by osteoblasts. As people age, resorption tends to outpace formation, so more bone is broken down than rebuilt. This net loss leads to decreased bone mineral density and weaker bones. That’s why the statement that bone breakdown exceeds bone formation best describes the aging change. The other options imply the opposite trend or no change, which doesn’t fit the aging pattern.

Bone remodeling is a balance between bone resorption by osteoclasts and bone formation by osteoblasts. As people age, resorption tends to outpace formation, so more bone is broken down than rebuilt. This net loss leads to decreased bone mineral density and weaker bones. That’s why the statement that bone breakdown exceeds bone formation best describes the aging change. The other options imply the opposite trend or no change, which doesn’t fit the aging pattern.

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